Synthesis of (Aza)n[3n]cyclophanes as host molecules

Hiroyuki Takemura, Masahiko Suenaga, Kiyoshi Sakai, Hisao Kawachi, Teruo Shinmyozu, Yuji Miyahara, Takahiko Inazu

Research output: Contribution to journalArticlepeer-review

36 Citations (Scopus)


(Aza)n[3n]cyclophanes were synthesized by the coupling reaction of p-toluenesulfonamide and bis(halomethyl) derivatives in the presence of a base (K2CO3, NaH etc.) using DMF, dioxane etc. as a solvent, in acceptable yields. Tetraaza macrocyclic compound (the dimer in Fig. 1) obtained by the coupling of 2,11-diaza[3.3]metacyclophane with 1,3-bis(bromomethyl)benzene gavea 1:1 adduct with benzene.

Original languageEnglish
Pages (from-to)207-214
Number of pages8
JournalJournal of Inclusion Phenomena
Issue number1-2
Publication statusPublished - Mar 1984

All Science Journal Classification (ASJC) codes

  • Condensed Matter Physics
  • Chemistry(all)


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