We have reported that SPG can from a complex with oligodeoxynucleotide (ODN) attaching (<A20) tail at 3′ end. However, SPG cannot form the complex with ODN attaching short tail (<dAso) due to reduction of thermodynamic stability. In this study, we examined whether ODN-conjugated SPG can form an intramolecular complex. dA20 was introduced to reducing terminal of SPG via diaminoalkanes or diaminoPEGs. The conjugates were purified by gel-filtration. CD spectrum of the conjugate indicated a formation of intramolecular complex.
|Number of pages||1|
|Publication status||Published - 2006|
|Event||55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan|
Duration: Sept 20 2006 → Sept 22 2006
|Other||55th Society of Polymer Science Japan Symposium on Macromolecules|
|Period||9/20/06 → 9/22/06|
All Science Journal Classification (ASJC) codes