TY - GEN
T1 - Synergistic electro-mechanical transfection for in-vivo regenerative therapy using electrically-induced microbubbles
AU - Hirao, Akiho
AU - Miwa, Keiko
AU - Moriizumi, Yasuhiro
AU - Yamanishi, Yoko
N1 - Publisher Copyright:
© 2019 CBMS-0001.
PY - 2019
Y1 - 2019
N2 - We have achieved permeabilization of adherent cells and gene transfer into them with a novel method using electrically-induced microbubbles [1]. Our technology has three remarkable points: (1) There is no safety concern which viral vectors always have. (2) Local permeabilization of living tissue can be achieved efficiently with minimal-invasiveness. (3) The size of the device is small and will be conveniently applied to a living body. This technology will contribute to realization of in-vivo regenerative therapy.
AB - We have achieved permeabilization of adherent cells and gene transfer into them with a novel method using electrically-induced microbubbles [1]. Our technology has three remarkable points: (1) There is no safety concern which viral vectors always have. (2) Local permeabilization of living tissue can be achieved efficiently with minimal-invasiveness. (3) The size of the device is small and will be conveniently applied to a living body. This technology will contribute to realization of in-vivo regenerative therapy.
UR - http://www.scopus.com/inward/record.url?scp=85094966655&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85094966655&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:85094966655
T3 - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
SP - 882
EP - 883
BT - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
PB - Chemical and Biological Microsystems Society
T2 - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
Y2 - 27 October 2019 through 31 October 2019
ER -