Surgical treatment of intrahepatic cholangiocarcinoma in the USA

Nir Lubezky, Marcelo Facciuto, Norifumi Harimoto, Myron E. Schwartz, Sander S. Florman

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)


Cholangiocarcinoma (CC) is a malignancy that arises from the epithelial cells of the biliary system (ductules as well as large ducts, and likely from progenitor cells, as well). Intrahepatic CC (ICC) is the second most common primary hepatic malignancy after hepatocellular carcinoma (HCC), and accounts for 10-15% of primary liver cancers. ICC differs from both extrahepatic and CC and HCC and has unique risk factors, histological features, genetic alterations and clinical outcomes. The natural history and results of surgical intervention are not well described as ICC is a relatively uncommon tumor, especially in the USA. This article reviews the literature relevant to the surgical management and outcome of patients with ICC in the USA.

Original languageEnglish
Pages (from-to)124-130
Number of pages7
JournalJournal of Hepato-Biliary-Pancreatic Sciences
Issue number2
Publication statusPublished - Feb 1 2015

All Science Journal Classification (ASJC) codes

  • Surgery
  • Hepatology


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