Supercritical Fluid Chromatography

Udi Jumhawan, Takeshi Bamba

    Research output: Chapter in Book/Report/Conference proceedingChapter

    7 Citations (Scopus)


    Supercritical fluid chromatography (SFC) is a separation technique that characteristically a hybrid of both gas chromatography (GC) and liquid chromatography (LC). With the favorable properties of green solvent supercritical carbon dioxide (SCCO2) as the main mobile phase, SFC has gained much attraction for analyzing and separating a wide range of compounds. Having remarkable sensitivity and selectivity, mass spectrometer (MS) is widely hyphenated to SFC system. SFC coupled to MS (SFC/MS) approach offers comprehensive lipid analysis that has not been resolved due to the complexity of lipid constituents and the existing isomers. Therefore, SFC/MS has more potential for application in lipidomics field compared to other analytical platforms. The prowess of SFC/MS technology as integral part of green chemistry has also been demonstrated in various fields from food science to biomedical research.

    Original languageEnglish
    Title of host publicationThe Application of Green Solvents in Separation Processes
    PublisherElsevier Inc.
    Number of pages34
    ISBN (Electronic)9780128054437
    ISBN (Print)9780128052976
    Publication statusPublished - Mar 22 2017

    All Science Journal Classification (ASJC) codes

    • Chemistry(all)
    • Environmental Science(all)


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