Supercritical Fluid Chromatography

Udi Jumhawan; Takeshi Bamba

doi:10.1016/B978-0-12-805297-6.00016-4

Supercritical Fluid Chromatography

Udi Jumhawan, Takeshi Bamba

Research output: Chapter in Book/Report/Conference proceeding › Chapter

7 Citations (Scopus)

Abstract

Supercritical fluid chromatography (SFC) is a separation technique that characteristically a hybrid of both gas chromatography (GC) and liquid chromatography (LC). With the favorable properties of green solvent supercritical carbon dioxide (SCCO₂) as the main mobile phase, SFC has gained much attraction for analyzing and separating a wide range of compounds. Having remarkable sensitivity and selectivity, mass spectrometer (MS) is widely hyphenated to SFC system. SFC coupled to MS (SFC/MS) approach offers comprehensive lipid analysis that has not been resolved due to the complexity of lipid constituents and the existing isomers. Therefore, SFC/MS has more potential for application in lipidomics field compared to other analytical platforms. The prowess of SFC/MS technology as integral part of green chemistry has also been demonstrated in various fields from food science to biomedical research.

Original language	English
Title of host publication	The Application of Green Solvents in Separation Processes
Publisher	Elsevier Inc.
Pages	483-516
Number of pages	34
ISBN (Electronic)	9780128054437
ISBN (Print)	9780128052976
DOIs	https://doi.org/10.1016/B978-0-12-805297-6.00016-4
Publication status	Published - Mar 22 2017

All Science Journal Classification (ASJC) codes

Chemistry(all)
Environmental Science(all)

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10.1016/B978-0-12-805297-6.00016-4

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title = "Supercritical Fluid Chromatography",

abstract = "Supercritical fluid chromatography (SFC) is a separation technique that characteristically a hybrid of both gas chromatography (GC) and liquid chromatography (LC). With the favorable properties of green solvent supercritical carbon dioxide (SCCO2) as the main mobile phase, SFC has gained much attraction for analyzing and separating a wide range of compounds. Having remarkable sensitivity and selectivity, mass spectrometer (MS) is widely hyphenated to SFC system. SFC coupled to MS (SFC/MS) approach offers comprehensive lipid analysis that has not been resolved due to the complexity of lipid constituents and the existing isomers. Therefore, SFC/MS has more potential for application in lipidomics field compared to other analytical platforms. The prowess of SFC/MS technology as integral part of green chemistry has also been demonstrated in various fields from food science to biomedical research.",

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AB - Supercritical fluid chromatography (SFC) is a separation technique that characteristically a hybrid of both gas chromatography (GC) and liquid chromatography (LC). With the favorable properties of green solvent supercritical carbon dioxide (SCCO2) as the main mobile phase, SFC has gained much attraction for analyzing and separating a wide range of compounds. Having remarkable sensitivity and selectivity, mass spectrometer (MS) is widely hyphenated to SFC system. SFC coupled to MS (SFC/MS) approach offers comprehensive lipid analysis that has not been resolved due to the complexity of lipid constituents and the existing isomers. Therefore, SFC/MS has more potential for application in lipidomics field compared to other analytical platforms. The prowess of SFC/MS technology as integral part of green chemistry has also been demonstrated in various fields from food science to biomedical research.

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ER -

Supercritical Fluid Chromatography

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