Sulfate Conjugation of Various Phenols by Liver-Soluble Fraction of Goldfish

Kunio Kobayashi, Shigeo Kimura, Yuji Oshima

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5 Citations (Scopus)


A study has been made of the capability of the sulfate conjugating enzyme system in the liver-soluble fraction from goldfish Carassius auratus, to phenol and twenty-one phenolic compounds as follows at various concentrations from 0.00067 to 33.3 mm in reaction media: (1) chlorophenols (o-;p-; 2,4-; 2,4,5-; 2,4,6-; 2,3,4,6-; 2,3,4,5,6-), (2) aminophenols (o-; p-), (3) nitrophenols (m-; o-; p-; 2,4-; 2,4,6-), (4) polyphenols (resorcinol; catechol; pyrogallol), (5) other phenols(p-cresol; o,o’- biphenol; phenolphthalein; phenol red). The liver-soluble fraction showed fairly high activities of the sulfate conjugation for half of the tested phenols corresponding to 53-116 % of that for phenol (246 nmol/h/g-liver), while the negligible conjugation for less than 5% of that for phenol was observed only in three phenols, i.e., 2,4-dinitrophenol, 2,4,6-trinitrophenol and phenol red. On the other hand, some phenols which showed low sulfate conjugation among the tested phenols such as pentachlorophenol strongly inhibited the sulfate conjugating enzyme system.

Original languageEnglish
Pages (from-to)833-837
Number of pages5
Issue number5
Publication statusPublished - 1984
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Aquatic Science


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