Studies on DNA dynamics using 2-N-tert-butylaminoxylpurines.

Mariko Aso, John Walter Mirc, Manami Kurita, Noboru Koga, Hiroshi Suemune

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


2-N-tert-Butylaminoxylpurines (1) and (2) were synthesized from 2'-deoxy-6-chloropurine derivative by lithiation strategy. Effects of motion of 1 and 2 on EPR spectra were studied by EPR measurement in sucrose solution at various temperatures. The single stranded and duplexed 15-mers containing 1 showed the clear difference in the EPR spectra to indicate 1 has the potential to accurately study the dynamics of purine residues.

Original languageEnglish
Pages (from-to)163-164
Number of pages2
JournalNucleic acids symposium series (2004)
Issue number51
Publication statusPublished - 2007

All Science Journal Classification (ASJC) codes

  • General Medicine


Dive into the research topics of 'Studies on DNA dynamics using 2-N-tert-butylaminoxylpurines.'. Together they form a unique fingerprint.

Cite this