TY - JOUR
T1 - Studies of human visual pathophysiology with visual evoked potentials
AU - Tobimatsu, Shozo
AU - Celesia, Gastone G.
N1 - Funding Information:
This study was supported in part by Grant-in-Aid for the 21st Century COE Program and Grant-in-Aid for Scientists, No 16390253 and No 16200005 from the Ministry of Education, Culture, Sports, Science and Technology in Japan.
PY - 2006/7
Y1 - 2006/7
N2 - Visual evoked potentials (VEPs) offer reproducible and quantitative data on the function of the visual pathways and the visual cortex. Pattern reversal VEPs to full-field stimulation are best suited to evaluate anterior visual pathways while hemi-field stimulation is most effective in the assessment of post-chiasmal function. However, visual information is processed simultaneously via multiple parallel channels and each channel constitutes a set of sequential processes. We outline the major parallel pathways of the visual system from the retina to the primary visual cortex and higher visual areas via lateral geniculate nucleus that receive visual input. There is no best method of stimulus selection, rather visual stimuli and VEPs' recording should be tailored to answer specific clinical and/or research questions. Newly developed techniques that can assess the functions of extrastriate as well as striate cortices are discussed. Finally, an algorithm of sequential steps to evaluate the various levels of visual processing is proposed and its clinical use revisited.
AB - Visual evoked potentials (VEPs) offer reproducible and quantitative data on the function of the visual pathways and the visual cortex. Pattern reversal VEPs to full-field stimulation are best suited to evaluate anterior visual pathways while hemi-field stimulation is most effective in the assessment of post-chiasmal function. However, visual information is processed simultaneously via multiple parallel channels and each channel constitutes a set of sequential processes. We outline the major parallel pathways of the visual system from the retina to the primary visual cortex and higher visual areas via lateral geniculate nucleus that receive visual input. There is no best method of stimulus selection, rather visual stimuli and VEPs' recording should be tailored to answer specific clinical and/or research questions. Newly developed techniques that can assess the functions of extrastriate as well as striate cortices are discussed. Finally, an algorithm of sequential steps to evaluate the various levels of visual processing is proposed and its clinical use revisited.
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U2 - 10.1016/j.clinph.2006.01.004
DO - 10.1016/j.clinph.2006.01.004
M3 - Review article
C2 - 16516551
AN - SCOPUS:33745340668
SN - 1388-2457
VL - 117
SP - 1414
EP - 1433
JO - Clinical Neurophysiology
JF - Clinical Neurophysiology
IS - 7
ER -