TY - JOUR
T1 - Structural changes in ribonuclease P RNA in the hyperthermophilic archaeon pyrococcus horikoshii OT3 induced on interaction with proteins
AU - Kosaka, Shunsuke
AU - Hada, Kazumasa
AU - Nakashima, Takashi
AU - Kimura, Makoto
N1 - Funding Information:
This work was supported in part by a grant-in-aid for scientific research from the Ministry of Education, Culture, Sports, Science, and Technology of Japan (no. 19380060, to M.K.).
PY - 2010
Y1 - 2010
N2 - The activated structure of RNase P RNA (PhopRNA) in Pyrococcus horikoshii OT3 was characterized by circular dichroism (CD) and ultraviolet (UV) absorb- ance spectra. The results suggested that interaction of four RNase P proteins (PhoPop5, PhoRpp21, PhoRpp29, and PhoRpp30) with PhopRNA results in destabilization of base stacking in PhopRNA, whereas the addition of a fifth protein, PhoRpp38, increases base stacking in PhopRNA.
AB - The activated structure of RNase P RNA (PhopRNA) in Pyrococcus horikoshii OT3 was characterized by circular dichroism (CD) and ultraviolet (UV) absorb- ance spectra. The results suggested that interaction of four RNase P proteins (PhoPop5, PhoRpp21, PhoRpp29, and PhoRpp30) with PhopRNA results in destabilization of base stacking in PhopRNA, whereas the addition of a fifth protein, PhoRpp38, increases base stacking in PhopRNA.
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U2 - 10.1271/bbb.90577
DO - 10.1271/bbb.90577
M3 - Article
C2 - 20139624
AN - SCOPUS:77249093991
SN - 0916-8451
VL - 74
SP - 394
EP - 396
JO - Bioscience, Biotechnology and Biochemistry
JF - Bioscience, Biotechnology and Biochemistry
IS - 2
ER -