Steroidal saponins from Asparagus acutifolius

Marc Sautour; Tomofumi Miyamoto; Marie Aleth Lacaille-Dubois

doi:10.1016/j.phytochem.2007.02.033

Steroidal saponins from Asparagus acutifolius

Marc Sautour, Tomofumi Miyamoto, Marie Aleth Lacaille-Dubois

Pharmaceutical Health Care and Sciences

Research output: Contribution to journal › Article › peer-review

36 Citations (Scopus)

Abstract

Six new steroidal saponins (1-6) were isolated from the roots of A. acutifolius L., together with a known spirostanol glycoside (7). Their structures were elucidated mainly by extensive spectroscopic analysis (1D and 2D NMR, FABMS and HRESIMS). Compounds 4-7 demonstrated antifungal activity against the human pathogenic yeasts C. albicans, C. glabrata and C. tropicalis with MICs values between 12.5 and 100 μg/ml.

Original language	English
Pages (from-to)	2554-2562
Number of pages	9
Journal	Phytochemistry
Volume	68
Issue number	20
DOIs	https://doi.org/10.1016/j.phytochem.2007.02.033
Publication status	Published - Oct 2007

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Biology
Plant Science
Horticulture

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10.1016/j.phytochem.2007.02.033

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abstract = "Six new steroidal saponins (1-6) were isolated from the roots of A. acutifolius L., together with a known spirostanol glycoside (7). Their structures were elucidated mainly by extensive spectroscopic analysis (1D and 2D NMR, FABMS and HRESIMS). Compounds 4-7 demonstrated antifungal activity against the human pathogenic yeasts C. albicans, C. glabrata and C. tropicalis with MICs values between 12.5 and 100 μg/ml.",

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Steroidal saponins from Asparagus acutifolius

Abstract

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