TY - JOUR
T1 - Steroid 5α-reductase inhibitory activity and hair regrowth effects of an extract from boehmeria nipononivea
AU - Shimizu, Kuniyoshi
AU - Kondo, Ryuichiro
AU - Sakai, Kokki
AU - Shoyama, Yoshihiro
AU - Sato, Hiroaki
AU - Ueno, Tetsuya
PY - 2000/1/1
Y1 - 2000/1/1
N2 - The acetone extract of Boehmeria nipononivea showed both potent 5α-reductase inhibitory activity and hair regrowth promotion effects on mice. 5α-Reductase inhibitory activity-guided fractionation led to six active fatty acids: α-linolenic, linoleic, palmitic, elaidic, oleic and stearic acids. The extract of B. nipononivea, and α-linolenic, elaidic and stearic acids exhibited a hair regrowth effect.
AB - The acetone extract of Boehmeria nipononivea showed both potent 5α-reductase inhibitory activity and hair regrowth promotion effects on mice. 5α-Reductase inhibitory activity-guided fractionation led to six active fatty acids: α-linolenic, linoleic, palmitic, elaidic, oleic and stearic acids. The extract of B. nipononivea, and α-linolenic, elaidic and stearic acids exhibited a hair regrowth effect.
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U2 - 10.1271/bbb.64.875
DO - 10.1271/bbb.64.875
M3 - Article
C2 - 10830511
AN - SCOPUS:0034171346
SN - 0916-8451
VL - 64
SP - 875
EP - 877
JO - Bioscience, Biotechnology and Biochemistry
JF - Bioscience, Biotechnology and Biochemistry
IS - 4
ER -