Spontaneous vesicle formation of mixtures of double-chain cationic surfactants with a different counterion

Makoto Aratono, Azusa Mori, Ikuyo Koga, Makiko Shigehisa, Nami Onimaru, Koji Tsuchiya, Takanori Takiue, Hiroki Matsubara

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


Aggregate formation of a didodecyldimethylammonium bromide (DDAB) and didodecyldimethylammonium chloride (DDAC) mixture in aqueous solution was investigated. The concentration vs composition diagram of aggregate formation was constructed by analyzing the surface tension, turbidity, and electrical conductivity data. The cryogenic transmission electron microscopy was applied to several representative points in the diagram and provided information of the morphology of aggregates. The sequence of monomer (m) - m + small aggregate (A) - m + A + vesicle (V) - m + V was concluded with increasing total concentration of surfactants at all mixing ratios. The compositions of counterions in A and V were estimated on the basis of thermodynamic consideration and examined from me viewpoint of asymmetry of constituents and uneven distribution between outer and inner monolayers of a vesicle bilayer. Vesicle surfaces were suggested to abound in chloride ions compared to bulk solution, which is opposite to spherical micelle surfaces.

Original languageEnglish
Pages (from-to)12304-12311
Number of pages8
JournalJournal of Physical Chemistry B
Issue number39
Publication statusPublished - Oct 2 2008

All Science Journal Classification (ASJC) codes

  • Physical and Theoretical Chemistry
  • Surfaces, Coatings and Films
  • Materials Chemistry


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