Spontaneous resolution of cystic hygroma and hydrops in a fetus with Noonan's syndrome

Asuka Kiyota, Kiyomi Tsukimori, Yasuo Yumoto, Satoshi Hojo, Seiichi Morokuma, Kotaro Fukushima, Yasushi Takahata, Hideki Nakayama, Norio Wake

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


Many studies have shown that the prognosis of cystic hygroma associated with hydrops fetalis is poor. We report a rare case of fetal cystic hygroma and hydrops fetalis that spontaneously resolved with subsequent delivery at 37 weeks of a living female infant with Noonan's syndrome. The prognostic significance of prenatal resolution of cystic hygroma and hydrops is uncertain. Serial evaluation of affected fetuses with ultrasound imaging may help clarify pathogenesis of cystic hygroma with associated hydrops, as well as mechanisms underlying spontaneous resolution.

Original languageEnglish
Pages (from-to)499-502
Number of pages4
JournalFetal Diagnosis and Therapy
Issue number4
Publication statusPublished - Jan 2009

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Embryology
  • Radiology Nuclear Medicine and imaging
  • Obstetrics and Gynaecology


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