Spin-labeled dendrimers in EPR imaging with low molecular weight nitroxides

Alexander T. Yordanov, Ken Ichi Yamada, Murali C. Krishna, James B. Mitchell, Eric Woller, Mary Cloninger, Martin W. Brechbiel

Research output: Contribution to journalArticlepeer-review

32 Citations (Scopus)


Sixth-generation PAMAM dendrimers labeled with 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO, shown schematically) have been synthesized and are shown to reoxidize EPR-silent hydroxylamines to EPR-active nitroxides. Therefore these dendrimers are potential TEMPO free radical life supporters for EPR imaging.

Original languageEnglish
Pages (from-to)2690-2692
Number of pages3
JournalAngewandte Chemie - International Edition
Issue number14
Publication statusPublished - Jul 16 2001
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Chemistry
  • Catalysis


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