Species differences in metabolism of a new antiepileptic drug candidate, DSP-0565 [2-(2′-fluoro[1,1′-biphenyl]-2-yl)acetamide]

Biochemistry, Genetics and Molecular Biology

• Metabolic Pathway 100%
• Animal 66%
• Enzymatic Hydrolysis 66%
• Rat 50%
• Human 50%
• Metabolite 50%
• Dog 50%
• Species Difference 50%
• Dose 33%
• Hepatocyte 33%
• Intrinsic Clearance 33%
• Alpha Oxidation 16%
• Contrast 16%
• Comprehension 16%
• Pharmacokinetics 16%
• Radioactivity 16%
• Benzene 16%
• Hydroxylation 16%
• Acetic Acid 16%
• Oral Clearance 16%
• Glucuronide 16%
• Primary Metabolite 16%
• Metabolic Clearance 16%

Immunology and Microbiology

• Metabolism 100%
• Animal 66%
• Hydrolysis 66%
• Human 50%
• Rat 50%
• Metabolite 50%
• Dog 50%
• Species Difference 50%
• Dose 33%
• Intrinsic Clearance 33%
• Contrast 16%
• Comprehension 16%
• Oxidation 16%
• Hydroxylation 16%
• Pharmacokinetics 16%
• Urine 16%
• Acetic Acid 16%
• Feces 16%
• Radioactivity 16%
• Benzene 16%
• Metabolic Clearance 16%
• Oral Clearance 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Animal 66%
• Rat 50%
• Human 50%
• Biphenyl 50%
• Dog 50%
• Anticonvulsive Agent 33%
• Carbon 14 33%
• Acetamide 33%
• Benzene 16%
• Pharmacokinetics 16%
• Potassium Acetate 16%
• Glucuronide 16%