Abstract
A sensitive and selective method has been developed for simultaneous determination of triazolam and its major metabolites, α-hydroxytriazolam and 4-hydroxytriazolam in human whole blood and urine. The drugs were effectively extracted using a 3-step solvent extraction procedure followed by tert-butyldimethylsilyl derivatization, and subjected to GC/MS in the negative ion chemical ionization mode.
| Original language | English |
|---|---|
| Pages (from-to) | 137-143 |
| Number of pages | 7 |
| Journal | Problems of Forensic Sciences |
| Volume | 43 |
| Publication status | Published - 2000 |
All Science Journal Classification (ASJC) codes
- Pathology and Forensic Medicine