TY - JOUR
T1 - Severe Infectious Mononucleosis-like Syndrome and Primary Human Herpesvirus 6 Infection in an Adult
AU - Akashi, Koichi
AU - Eizuru, Yoshito
AU - Sumiyoshi, Yoshiaki
AU - Minematsu, Toshio
AU - Hara, Sachiko
AU - Harada, Mine
AU - Kikuchi, Masahiro
AU - Niho, Yoshiyuki
AU - Minamishima, Yoichi
PY - 1993/7/15
Y1 - 1993/7/15
N2 - Human herpesvirus 6 (HHV-6) was first isolated from patients with the acquired immunodeficiency syndrome or lymphoproliferative diseases and was named human B-lymphotropic virus1. However, later studies revealed that the virus is T-lymphotropic in vitro2 and in vivo3. Recently, two genotypes of HHV-6 (type A and type B) have been distinguished on the basis of their restriction polymorphism4–6. HHV-6 has been identified as the etiologic agent of exanthem subitum in infants,7 and an acute febrile illness in young children8. Most people are seropositive for HHV-6 by the age of three years9,10. HHV-6 also produces…
AB - Human herpesvirus 6 (HHV-6) was first isolated from patients with the acquired immunodeficiency syndrome or lymphoproliferative diseases and was named human B-lymphotropic virus1. However, later studies revealed that the virus is T-lymphotropic in vitro2 and in vivo3. Recently, two genotypes of HHV-6 (type A and type B) have been distinguished on the basis of their restriction polymorphism4–6. HHV-6 has been identified as the etiologic agent of exanthem subitum in infants,7 and an acute febrile illness in young children8. Most people are seropositive for HHV-6 by the age of three years9,10. HHV-6 also produces…
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U2 - 10.1056/NEJM199307153290304
DO - 10.1056/NEJM199307153290304
M3 - Article
C2 - 8390615
AN - SCOPUS:0027230447
SN - 0028-4793
VL - 329
SP - 168
EP - 171
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 3
ER -
