Sequential occurrence of non-small cell and small cell lung cancer with the same EGFR mutation

Ryotaro Morinaga; Isamu Okamoto; Kazuyuki Furuta; Yukiko Kawano; Masaru Sekijima; Kensaku Dote; Takao Satou; Kazuto Nishio; Masahiro Fukuoka; Kazuhiko Nakagawa

doi:10.1016/j.lungcan.2007.05.014

Sequential occurrence of non-small cell and small cell lung cancer with the same EGFR mutation

Ryotaro Morinaga, Isamu Okamoto, Kazuyuki Furuta, Yukiko Kawano, Masaru Sekijima, Kensaku Dote, Takao Satou, Kazuto Nishio, Masahiro Fukuoka, Kazuhiko Nakagawa

Research output: Contribution to journal › Article › peer-review

98 Citations (Scopus)

Abstract

We report a case of small cell lung cancer (SCLC) developing after prolonged treatment (more than 2 years) for primary adenocarcinoma of the lung, and we show that both the SCLC and non-small cell lung cancer (NSCLC) tissues obtained from the same site share the same deletion in exon 19 of EGFR. This case suggests that the activating EGFR mutations may confer the pathogenesis of a subset of SCLC.

Original language	English
Pages (from-to)	411-413
Number of pages	3
Journal	Lung Cancer
Volume	58
Issue number	3
DOIs	https://doi.org/10.1016/j.lungcan.2007.05.014
Publication status	Published - Dec 2007
Externally published	Yes

All Science Journal Classification (ASJC) codes

Oncology
Pulmonary and Respiratory Medicine
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.lungcan.2007.05.014

Cite this

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title = "Sequential occurrence of non-small cell and small cell lung cancer with the same EGFR mutation",

abstract = "We report a case of small cell lung cancer (SCLC) developing after prolonged treatment (more than 2 years) for primary adenocarcinoma of the lung, and we show that both the SCLC and non-small cell lung cancer (NSCLC) tissues obtained from the same site share the same deletion in exon 19 of EGFR. This case suggests that the activating EGFR mutations may confer the pathogenesis of a subset of SCLC.",

author = "Ryotaro Morinaga and Isamu Okamoto and Kazuyuki Furuta and Yukiko Kawano and Masaru Sekijima and Kensaku Dote and Takao Satou and Kazuto Nishio and Masahiro Fukuoka and Kazuhiko Nakagawa",

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doi = "10.1016/j.lungcan.2007.05.014",

language = "English",

volume = "58",

pages = "411--413",

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T1 - Sequential occurrence of non-small cell and small cell lung cancer with the same EGFR mutation

AU - Morinaga, Ryotaro

AU - Okamoto, Isamu

AU - Furuta, Kazuyuki

AU - Kawano, Yukiko

AU - Sekijima, Masaru

AU - Dote, Kensaku

AU - Satou, Takao

AU - Nishio, Kazuto

AU - Fukuoka, Masahiro

AU - Nakagawa, Kazuhiko

PY - 2007/12

Y1 - 2007/12

N2 - We report a case of small cell lung cancer (SCLC) developing after prolonged treatment (more than 2 years) for primary adenocarcinoma of the lung, and we show that both the SCLC and non-small cell lung cancer (NSCLC) tissues obtained from the same site share the same deletion in exon 19 of EGFR. This case suggests that the activating EGFR mutations may confer the pathogenesis of a subset of SCLC.

AB - We report a case of small cell lung cancer (SCLC) developing after prolonged treatment (more than 2 years) for primary adenocarcinoma of the lung, and we show that both the SCLC and non-small cell lung cancer (NSCLC) tissues obtained from the same site share the same deletion in exon 19 of EGFR. This case suggests that the activating EGFR mutations may confer the pathogenesis of a subset of SCLC.

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UR - http://www.scopus.com/inward/citedby.url?scp=35748973894&partnerID=8YFLogxK

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AN - SCOPUS:35748973894

SN - 0169-5002

VL - 58

SP - 411

EP - 413

JO - Lung Cancer

JF - Lung Cancer

IS - 3

ER -

Sequential occurrence of non-small cell and small cell lung cancer with the same EGFR mutation

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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