Sensing of oligopeptides using alternatively-deposited gold nanorods for surface-assisted laser desorption/ionization time-of-flight mass spectrometry

Masanori Fujii; Naotoshi Nakashima; Yasuro Niidome

doi:10.1557/opl.2012.379

Sensing of oligopeptides using alternatively-deposited gold nanorods for surface-assisted laser desorption/ionization time-of-flight mass spectrometry

Masanori Fujii
, Naotoshi Nakashima
, Yasuro Niidome

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Gold nanorods (NRs) were fixed on an ITO plate and used for the Surface-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (SALDI-MS) of oligopeptides (angiotensin I). The SALDI-MS measurements had a high sensitivity to the angiotensin on the ITO plate on which isolated NRs were deposited. Angiotensin molecules in a very diluted solution (1 × 10 ^-11 M) could be detected at m/z = 1297 with a good signal/noise ratio (S/N = 18). In contrast, alternatively deposited NR an ITO plate, which present broad surface plasmon bands, was found to be inactive for SALDI measurements.

Original language	English
Title of host publication	Gels and Biomedical Materials
Pages	145-149
Number of pages	5
DOIs	https://doi.org/10.1557/opl.2012.379
Publication status	Published - 2012
Event	2011 MRS Fall Meeting - Boston, MA, United States Duration: Nov 28 2011 → Dec 2 2011

Publication series

Name	Materials Research Society Symposium Proceedings
Volume	1418
ISSN (Print)	0272-9172

Other

Other	2011 MRS Fall Meeting
Country/Territory	United States
City	Boston, MA
Period	11/28/11 → 12/2/11

All Science Journal Classification (ASJC) codes

General Materials Science
Condensed Matter Physics
Mechanics of Materials
Mechanical Engineering

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10.1557/opl.2012.379

Cite this

Sensing of oligopeptides using alternatively-deposited gold nanorods for surface-assisted laser desorption/ionization time-of-flight mass spectrometry. / Fujii, Masanori; Nakashima, Naotoshi; Niidome, Yasuro.
Gels and Biomedical Materials. 2012. p. 145-149 (Materials Research Society Symposium Proceedings; Vol. 1418).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Fujii, M, Nakashima, N & Niidome, Y 2012, Sensing of oligopeptides using alternatively-deposited gold nanorods for surface-assisted laser desorption/ionization time-of-flight mass spectrometry. in Gels and Biomedical Materials. Materials Research Society Symposium Proceedings, vol. 1418, pp. 145-149, 2011 MRS Fall Meeting, Boston, MA, United States, 11/28/11. https://doi.org/10.1557/opl.2012.379

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title = "Sensing of oligopeptides using alternatively-deposited gold nanorods for surface-assisted laser desorption/ionization time-of-flight mass spectrometry",

abstract = "Gold nanorods (NRs) were fixed on an ITO plate and used for the Surface-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (SALDI-MS) of oligopeptides (angiotensin I). The SALDI-MS measurements had a high sensitivity to the angiotensin on the ITO plate on which isolated NRs were deposited. Angiotensin molecules in a very diluted solution (1 × 10 -11 M) could be detected at m/z = 1297 with a good signal/noise ratio (S/N = 18). In contrast, alternatively deposited NR an ITO plate, which present broad surface plasmon bands, was found to be inactive for SALDI measurements.",

author = "Masanori Fujii and Naotoshi Nakashima and Yasuro Niidome",

note = "Funding Information: This work was supported by a Grant-in-Aid for Scientific Research (B) (No. 21350110) (for NN), Grant-in-Aid for Scientific Research (B) (No. 21651053) (for YN), Grant-in-Aid for JSPS Fellows (No. 222032) (for YK) and the Global COE Program “Science for Future Molecular Systems” from the Ministry of Education, Culture, Sports, Science and Technology, Japan.; 2011 MRS Fall Meeting ; Conference date: 28-11-2011 Through 02-12-2011",

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doi = "10.1557/opl.2012.379",

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series = "Materials Research Society Symposium Proceedings",

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AU - Fujii, Masanori

AU - Nakashima, Naotoshi

AU - Niidome, Yasuro

N1 - Funding Information: This work was supported by a Grant-in-Aid for Scientific Research (B) (No. 21350110) (for NN), Grant-in-Aid for Scientific Research (B) (No. 21651053) (for YN), Grant-in-Aid for JSPS Fellows (No. 222032) (for YK) and the Global COE Program “Science for Future Molecular Systems” from the Ministry of Education, Culture, Sports, Science and Technology, Japan.

PY - 2012

Y1 - 2012

N2 - Gold nanorods (NRs) were fixed on an ITO plate and used for the Surface-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (SALDI-MS) of oligopeptides (angiotensin I). The SALDI-MS measurements had a high sensitivity to the angiotensin on the ITO plate on which isolated NRs were deposited. Angiotensin molecules in a very diluted solution (1 × 10 -11 M) could be detected at m/z = 1297 with a good signal/noise ratio (S/N = 18). In contrast, alternatively deposited NR an ITO plate, which present broad surface plasmon bands, was found to be inactive for SALDI measurements.

AB - Gold nanorods (NRs) were fixed on an ITO plate and used for the Surface-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (SALDI-MS) of oligopeptides (angiotensin I). The SALDI-MS measurements had a high sensitivity to the angiotensin on the ITO plate on which isolated NRs were deposited. Angiotensin molecules in a very diluted solution (1 × 10 -11 M) could be detected at m/z = 1297 with a good signal/noise ratio (S/N = 18). In contrast, alternatively deposited NR an ITO plate, which present broad surface plasmon bands, was found to be inactive for SALDI measurements.

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U2 - 10.1557/opl.2012.379

DO - 10.1557/opl.2012.379

M3 - Conference contribution

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SN - 9781605113951

T3 - Materials Research Society Symposium Proceedings

SP - 145

EP - 149

BT - Gels and Biomedical Materials

T2 - 2011 MRS Fall Meeting

Y2 - 28 November 2011 through 2 December 2011

ER -

Sensing of oligopeptides using alternatively-deposited gold nanorods for surface-assisted laser desorption/ionization time-of-flight mass spectrometry

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