Self-assembled synthetic viral capsids from a 24-mer viral peptide fragment

Kazunori Matsuura; Kenta Watanabe; Tsubasa Matsuzaki; Kazuo Sakurai; Nobuo Kimizuka

doi:10.1002/anie.201004606

Self-assembled synthetic viral capsids from a 24-mer viral peptide fragment

Kazunori Matsuura, Kenta Watanabe, Tsubasa Matsuzaki, Kazuo Sakurai, Nobuo Kimizuka

Research output: Contribution to journal › Article › peer-review

100 Citations (Scopus)

Abstract

Assemble a virus: A chemical strategy to de novo design "tailor-made" viruslike nanocapsules was developed (see picture). 24-mer β-annulus peptides of the tomato bushy stunt virus (TBSV) spontaneously self-assemble into hollow nanocapsules with a size of 30-50 nm. The hollow structure of the assemblies was clearly revealed by small-angle X-ray scattering (SAXS).

Original language	English
Pages (from-to)	9662-9665
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	49
Issue number	50
DOIs	https://doi.org/10.1002/anie.201004606
Publication status	Published - Dec 10 2010

All Science Journal Classification (ASJC) codes

Catalysis
Chemistry(all)

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10.1002/anie.201004606

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AU - Watanabe, Kenta

AU - Matsuzaki, Tsubasa

AU - Sakurai, Kazuo

AU - Kimizuka, Nobuo

PY - 2010/12/10

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Self-assembled synthetic viral capsids from a 24-mer viral peptide fragment

Abstract

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