Selectively induced apoptosis in human neutrophils in the presence of oxidative phenoxazines, 2-amino-4,4α-dihydryo-4α-7H-phenoxazine-3- one and 2-aminophenoxazine-3-one, preceded by decrease of intracellular pH, depolarization of the mitochondria, and inhibition of superoxide generation

Takanobu Tabuchi, Xiao Fang Che, Katsuya Hiraishi, Masakazu Adachi, Kei Miyano, Hideki Sumimoto, Takafumi Tabuchi, Keisuke Miyazawa, Akio Tomoda

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Chemistry

Pharmacology, Toxicology and Pharmaceutical Science