Selective oxidation of alcohol-d1to aldehyde-d1using MnO2

Hironori Okamura, Yoko Yasuno, Atsushi Nakayama, Katsushi Kumadaki, Kohei Kitsuwa, Keita Ozawa, Yusaku Tamura, Yuki Yamamoto, Tetsuro Shinada

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


The selective oxidation of alcohol-d1to prepare aldehyde-d1was newly developed by means of NaBD4reduction/activated MnO2oxidation. Various aldehyde-d1derivatives including aromatic and unsaturated aldehyde-d1can be prepared with a high deuterium incorporation ratio (up to 98% D). Halogens (chloride, bromide, and iodide), alkene, alkyne, ester, nitro, and cyano groups in the substrates are tolerated under the mild conditions.

Original languageEnglish
Pages (from-to)28530-28534
Number of pages5
JournalRSC Advances
Issue number46
Publication statusPublished - Aug 16 2021
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Chemistry
  • General Chemical Engineering


Dive into the research topics of 'Selective oxidation of alcohol-d1to aldehyde-d1using MnO2'. Together they form a unique fingerprint.

Cite this