Selective cross-linking to the adenine of the TA interrupting site within the triple helix

Fumi Nagatsugi; Yoshihisa Matsuyama; Minoru Maeda; Shigeki Sasaki

doi:10.1016/S0960-894X(01)00783-1

Selective cross-linking to the adenine of the TA interrupting site within the triple helix

Fumi Nagatsugi
, Yoshihisa Matsuyama
, Minoru Maeda
, Shigeki Sasaki

Chemo-Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

The triplex-forming oligonucleotide incorporating the new nucleoside derivative (2) that connects the 2-amino-6-vinylpurine moiety to the 2-deoxyribose unit with an ethyl spacer has exhibited highly selective cross-linking reaction to the adenine of the TA interrupting site within the triple helix.

Original language	English
Pages (from-to)	487-489
Number of pages	3
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	12
Issue number	3
DOIs	https://doi.org/10.1016/S0960-894X(01)00783-1
Publication status	Published - Feb 11 2002

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

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10.1016/S0960-894X(01)00783-1

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title = "Selective cross-linking to the adenine of the TA interrupting site within the triple helix",

abstract = "The triplex-forming oligonucleotide incorporating the new nucleoside derivative (2) that connects the 2-amino-6-vinylpurine moiety to the 2-deoxyribose unit with an ethyl spacer has exhibited highly selective cross-linking reaction to the adenine of the TA interrupting site within the triple helix.",

author = "Fumi Nagatsugi and Yoshihisa Matsuyama and Minoru Maeda and Shigeki Sasaki",

note = "Funding Information: This work was supported by a Grant-in-Aid for Scientific Research (C), [Priority Area (A)(2)], from the Ministry of Education, Science, Sports, Science and Technology, Japan.",

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AU - Nagatsugi, Fumi

AU - Matsuyama, Yoshihisa

AU - Maeda, Minoru

AU - Sasaki, Shigeki

N1 - Funding Information: This work was supported by a Grant-in-Aid for Scientific Research (C), [Priority Area (A)(2)], from the Ministry of Education, Science, Sports, Science and Technology, Japan.

PY - 2002/2/11

Y1 - 2002/2/11

N2 - The triplex-forming oligonucleotide incorporating the new nucleoside derivative (2) that connects the 2-amino-6-vinylpurine moiety to the 2-deoxyribose unit with an ethyl spacer has exhibited highly selective cross-linking reaction to the adenine of the TA interrupting site within the triple helix.

AB - The triplex-forming oligonucleotide incorporating the new nucleoside derivative (2) that connects the 2-amino-6-vinylpurine moiety to the 2-deoxyribose unit with an ethyl spacer has exhibited highly selective cross-linking reaction to the adenine of the TA interrupting site within the triple helix.

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U2 - 10.1016/S0960-894X(01)00783-1

DO - 10.1016/S0960-894X(01)00783-1

M3 - Article

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JF - Bioorganic and Medicinal Chemistry Letters

IS - 3

ER -

Selective cross-linking to the adenine of the TA interrupting site within the triple helix

Abstract

All Science Journal Classification (ASJC) codes

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