Sclerosing epithelioid fibrosarcoma of the liver infiltrating the inferior vena cava

Yoshito Tomimaru, Hiroaki Nagano, Shigeru Marubashi, Shogo Kobayashi, Hidetoshi Eguchi, Yutaka Takeda, Masahiro Tanemura, Toru Kitagawa, Koji Umeshita, Nobuyuki Hashimoto, Hideki Yoshikawa, Kenichi Wakasa, Yuichiro Doki, Masaki Mori

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27 Citations (Scopus)


Sclerosing epithelioid fibrosarcoma (SEF) is a rare and distinct variant of fibrosarcoma, composed of epithelioid tumor cells arranged in strands, nests, cords, or sheets embedded within a sclerotic collagenous matrix. We report a 39-year-old man with SEF of the liver, which infiltrated the inferior vena cava (IVC). The SEF of the liver was successfully resected, and the infiltrated IVC was also removed together with the liver tumor. Histopathological examination of the tumor showed typical histopathology of SEF. Immunohistochemically, the tumor was positive for vimentin. Recurrence was noted 7 mo after surgery. After chemotherapy, the recurrent tumor was resected surgically, and histopathological examination showed similar findings to those of the primary tumor. To our knowledge, this is the first report of SEF of the liver with tumor invasion of the IVC.

Original languageEnglish
Pages (from-to)4204-4208
Number of pages5
JournalWorld Journal of Gastroenterology
Issue number33
Publication statusPublished - 2009
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Gastroenterology


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