Rotihibins, Novel Plant Growth Regulators from Streptomyces graminofaciens

Naoyuki Fukuchi, Kazuo Furihata, Jiro Nakayama, Akira Isogai

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


In the course of screening search for plant growth regulators, a culture filtrate of Streptomyces graminofaciens 3C02 was found to inhibit the growth of lettuce seedlings. The active substances, named rotihibin A (1) and B (2), were revealed to be lipo-peptidal compounds. Rotihibins inhibit growth of various plants at below 1 μg/ml, but do not show lethal activity even at higher doses.

Original languageEnglish
Pages (from-to)1004-1010
Number of pages7
JournalThe Journal of Antibiotics
Issue number9
Publication statusPublished - 1995
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery


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