Rhodium-catalyzed asymmetric synthesis of spirosilabifluorene derivatives

Yoichiro Kuninobu; Kanae Yamauchi; Naoya Tamura; Takayuki Seiki; Kazuhiko Takai

doi:10.1002/anie.201207723

Rhodium-catalyzed asymmetric synthesis of spirosilabifluorene derivatives

Yoichiro Kuninobu, Kanae Yamauchi, Naoya Tamura, Takayuki Seiki, Kazuhiko Takai

Research output: Contribution to journal › Article › peer-review

198 Citations (Scopus)

Abstract

Si goes chiral: Treatment of a bis(biphenyl)silane with a catalytic amount of a rhodium complex gave a spirosilabifluorene bearing a quaternary silicon atom. By using a rhodium catalyst with a chiral phosphine ligand (see scheme), asymmetric dehydrogenative cyclization proceeded to give chiral derivatives in good yields and enantioselectivities.

Original language	English
Pages (from-to)	1520-1522
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	52
Issue number	5
DOIs	https://doi.org/10.1002/anie.201207723
Publication status	Published - Jan 28 2013
Externally published	Yes

All Science Journal Classification (ASJC) codes

Catalysis
Chemistry(all)

Access to Document

10.1002/anie.201207723

Cite this

@article{f61cb7e5f023436d967c6e2ccdad9dfc,

title = "Rhodium-catalyzed asymmetric synthesis of spirosilabifluorene derivatives",

abstract = "Si goes chiral: Treatment of a bis(biphenyl)silane with a catalytic amount of a rhodium complex gave a spirosilabifluorene bearing a quaternary silicon atom. By using a rhodium catalyst with a chiral phosphine ligand (see scheme), asymmetric dehydrogenative cyclization proceeded to give chiral derivatives in good yields and enantioselectivities.",

author = "Yoichiro Kuninobu and Kanae Yamauchi and Naoya Tamura and Takayuki Seiki and Kazuhiko Takai",

year = "2013",

month = jan,

day = "28",

doi = "10.1002/anie.201207723",

language = "English",

volume = "52",

pages = "1520--1522",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "John Wiley and Sons Ltd",

number = "5",

}

TY - JOUR

T1 - Rhodium-catalyzed asymmetric synthesis of spirosilabifluorene derivatives

AU - Kuninobu, Yoichiro

AU - Yamauchi, Kanae

AU - Tamura, Naoya

AU - Seiki, Takayuki

AU - Takai, Kazuhiko

PY - 2013/1/28

Y1 - 2013/1/28

N2 - Si goes chiral: Treatment of a bis(biphenyl)silane with a catalytic amount of a rhodium complex gave a spirosilabifluorene bearing a quaternary silicon atom. By using a rhodium catalyst with a chiral phosphine ligand (see scheme), asymmetric dehydrogenative cyclization proceeded to give chiral derivatives in good yields and enantioselectivities.

AB - Si goes chiral: Treatment of a bis(biphenyl)silane with a catalytic amount of a rhodium complex gave a spirosilabifluorene bearing a quaternary silicon atom. By using a rhodium catalyst with a chiral phosphine ligand (see scheme), asymmetric dehydrogenative cyclization proceeded to give chiral derivatives in good yields and enantioselectivities.

UR - http://www.scopus.com/inward/record.url?scp=84872864159&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84872864159&partnerID=8YFLogxK

U2 - 10.1002/anie.201207723

DO - 10.1002/anie.201207723

M3 - Article

C2 - 23239057

AN - SCOPUS:84872864159

SN - 1433-7851

VL - 52

SP - 1520

EP - 1522

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 5

ER -

Rhodium-catalyzed asymmetric synthesis of spirosilabifluorene derivatives

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this