Retinoblastoma in children of advanced age

Kumiyo Oba, Hiroshi Yoshikawa, Ri Ichiro Kohno, Kumiko Kano, Yusuke Murakami, Tokiko Yamanaka, Noriko Yoshida, Tatsuro Ishibashi

Research output: Contribution to journalReview articlepeer-review


Purpose: To report 3 children who developed retinoblastoma with atypical clinical manifestations at the age of 8 years each. Cases: All the 3 cases were girls and were unilaterally affected. One case had hyperemia of affected eye as chief complaint. Her left eye simulated uveitis with visual acuity of 1.5. The other 2 cases showed vitreous opacity or hemorrhage with visual acuity of hand motion. Diagnostic imaging showed no intraocular tumor or calcification in all the cases. Enucleation led to the diagnosis of retinoblastoma with vitreous dissemination in the 3 cases. There has been no recurrence or metastasis during the follow-up for 16 months, 4 years and 7 years respectively. Conclusion: The present cases illustrate that retinoblastoma in children of advanced age may show atypical clinical manifestations. This particular feature needs due attention.

Original languageEnglish
Pages (from-to)1275-1279
Number of pages5
JournalJapanese Journal of Clinical Ophthalmology
Issue number8
Publication statusPublished - 2009

All Science Journal Classification (ASJC) codes

  • Ophthalmology


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