TY - JOUR
T1 - Repetitive transcranial magnetic stimulation of human MT+ reduces apparent motion perception
AU - Matsuyoshi, Daisuke
AU - Hirose, Nobuyuki
AU - Mima, Tatsuya
AU - Fukuyama, Hidenao
AU - Osaka, Naoyuki
N1 - Funding Information:
We wish to thank Mitsunari Abe for technical assistance. This study is partly supported by the Grants-in-Aid for Scientific Research on Priority Areas (Integrative Brain Research) for T.M. (18019020) and (System study on higher-order brain functions) for H.F. (18020014) from the MEXT of Japan, Grant-in-Aid for Scientific Research (C) 18500239 for T.M. and Grant-in-Aid for Scientific Research (A) 16203037 from Japan Society for the Promotion of Science for N.O.
PY - 2007/12/18
Y1 - 2007/12/18
N2 - We investigated the effects of repetitive transcranial magnetic stimulation (rTMS) over the human cerebral cortex on apparent motion perception. Previous studies have shown that human extrastriate visual area MT+ (V5) processes not only real but also apparent motion. However, the functional relevance of MT+ on long-range apparent motion perception remains unclear. Here, we show direct evidence for the involvement of MT+ in apparent motion perception using rTMS, which is known to temporarily inhibit a localized region in the cerebral cortex. The results showed that apparent motion perception decreased after applying rTMS over MT+, but not after applying rTMS over the control region (inferior temporal gyrus). The decrease in performance caused by applying rTMS to MT+ suggests that MT+ is a causally responsible region for apparent motion perception, and thus, further supports the idea that MT+ plays a major role in the perception of motion.
AB - We investigated the effects of repetitive transcranial magnetic stimulation (rTMS) over the human cerebral cortex on apparent motion perception. Previous studies have shown that human extrastriate visual area MT+ (V5) processes not only real but also apparent motion. However, the functional relevance of MT+ on long-range apparent motion perception remains unclear. Here, we show direct evidence for the involvement of MT+ in apparent motion perception using rTMS, which is known to temporarily inhibit a localized region in the cerebral cortex. The results showed that apparent motion perception decreased after applying rTMS over MT+, but not after applying rTMS over the control region (inferior temporal gyrus). The decrease in performance caused by applying rTMS to MT+ suggests that MT+ is a causally responsible region for apparent motion perception, and thus, further supports the idea that MT+ plays a major role in the perception of motion.
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U2 - 10.1016/j.neulet.2007.10.002
DO - 10.1016/j.neulet.2007.10.002
M3 - Article
C2 - 17997041
AN - SCOPUS:36348936650
SN - 0304-3940
VL - 429
SP - 131
EP - 135
JO - Neuroscience Letters
JF - Neuroscience Letters
IS - 2-3
ER -