TY - GEN
T1 - Reperfusion of micro-vascular occlusion by physical stimuli of electrically-induced
AU - Matsumura, D.
AU - Sumimoto, M.
AU - Miwa, K.
AU - Moriizumi, Y.
AU - Oh, H.
AU - Yamanishi, Y.
N1 - Funding Information:
This work was supported by JSPS KAKENHI Grant Number JP16H04307, JP17K18857 and Medical Research and Development Programs Focused on Technology Transfers: Development of Advanced Measurement and Analysis Systems (AMED-SENTAN), Japan Agency for Medical Research and development, AMED grant Number JP17hm0102049.Also in this study, we are grateful to Mr. Moriizumi of BEX Inc. for valuable advices about high frequency pulse etc.
Publisher Copyright:
Copyright © (2018) by Chemical and Biological Microsystems Society. All rights reserved.
PY - 2018
Y1 - 2018
N2 - A novel treatment of the retina vein occlusion by using electrically-induced bubble injector is proposed. This treatment provides physical stimuli to blood clot for reperfusion by microbubbles. These microbubbles occurred at the tip of electrically-induced bubble injector which has directivity. For the present study, the neovascular of the chicken embryo was employed as a retina vein occlusion phantom because their diameter is similar size. We have successfully produced a blood clot and blocked blood flow artificially at the vascular of the chicken embryo. We have successfully provided local physical stimuli to blood clot by microbubbles and confirmed the reperfusion.
AB - A novel treatment of the retina vein occlusion by using electrically-induced bubble injector is proposed. This treatment provides physical stimuli to blood clot for reperfusion by microbubbles. These microbubbles occurred at the tip of electrically-induced bubble injector which has directivity. For the present study, the neovascular of the chicken embryo was employed as a retina vein occlusion phantom because their diameter is similar size. We have successfully produced a blood clot and blocked blood flow artificially at the vascular of the chicken embryo. We have successfully provided local physical stimuli to blood clot by microbubbles and confirmed the reperfusion.
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M3 - Conference contribution
AN - SCOPUS:85079799190
T3 - 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
SP - 1985
EP - 1987
BT - 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
PB - Chemical and Biological Microsystems Society
T2 - 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Y2 - 11 November 2018 through 15 November 2018
ER -