Relieving pain and distress during venipuncture: Pilot study of the Japan Environment and Children's Study (JECS)

Kiwako Yamamoto-Hanada, Masaki Futamura, Hiroshi Kitazawa, Yukihiro Ohya, Fumio Kobayashi, Takeshi Kusuda, Masafumi Sanefuji, Masako Oda, Hiroshi Mitsubuchi, Eiji Shibata, Mayumi Tsuji, Fujio Kayama, Yuko Nakano, Eiko Suda, Takehiro Michikawa, Takahiko Katoh, Hirohisa Saito

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


Pain management for needle-related procedures is poor in Japan. In many countries the use of lidocaine/prilocaine cream for the relief of pain associated with venipuncture has been approved. In children, a psychological approach has also been shown to be effective in reducing pain with venipuncture. We developed a multidisciplinary procedure that combines a cream (2.5% lidocaine and 2.5% prilocaine) and pharmacological approaches such as preparation, education, positioning and distraction. We evaluated the feasibility and acceptability of the procedure for young children. Among 132 pediatric participants, 58.3% did not cry during venipuncture. According to caregiver questionnaire, 71.9% felt that the multidisciplinary procedure eliminated the fear of needle-related procedures in the children; 90.9% were satisfied with it and 75.8% thought it should be applied to all children undergoing venipuncture. The present results suggest that the multidisciplinary procedure is feasible, acceptable and suitable for use in children undergoing venipuncture.

Original languageEnglish
Pages (from-to)1044-1047
Number of pages4
JournalPediatrics International
Issue number5
Publication statusPublished - Oct 2015
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health


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