Recurrent Hopkin's syndrome: A case report and review of the literature

Pavone Piero, Maria Roberta Longo, Ferdinando Scalia, Riccardo Polosa, Jun Ichi Kira, Raffaele Falsaperla

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)


Flaccid paralysis affecting one or more limbs after an asthma attack is a poliomyelitis-like illness known as Hopkins' syndrome (HS). Although a viral infection or multifactorial immune suppression during an acute attack of bronchial asthma has been proposed to be the mechanism involved in this syndrome, the precise etiopathogenetic mechanism remains unknown. We report a 13-year-old girl who had recurrent acute episodes of myelitis after asthma attacks. She had four episodes of acute flaccid paralysis, each of which was preceded by acute asthma attacks. Some of the attacks were accompanied by sensory and sphincter disturbances. She had hyperIgEaemia and the prick test to Dermatophagoides farinae and cedar pollen was strongly positive. The present case is the first HS case demonstrating frequent recurrences and suggests a possible link between HS and atopic myelitis.

Original languageEnglish
Pages (from-to)89-91
Number of pages3
JournalJournal of the Neurological Sciences
Issue number1-2
Publication statusPublished - Oct 15 2010

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology


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