Recurrence of biphenotypic sinonasal sarcoma with cerebral hemorrhaging

Hirotaka Fudaba, Yasutomo Momii, Takashi Hirano, Hidetaka Yamamoto, Minoru Fujiki

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3 Citations (Scopus)


Biphenotypic sinonasal sarcoma (BSNS) is a newly classified tumor that is characterized by neural and myogenic differentiation. The authors herein report a rare patient of the recurrence of BSNS with intracranial hemorrhaging and a review of the literature. A 70-year-old man presented with disturbance of consciousness and vomiting blood. He had undergone resection of a sinonasal tumor 11 years earlier and shown no recurrence at his last follow-up 4 years ago. Computed tomography showed cerebral hemorrhaging around a low-density mass that occupied the left frontal base and left ethmoid sinus. Total resection was performed. A histological examination of tumor specimens obtained from the first and the second resections revealed almost the same characteristic morphological features and the patient was diagnosed with BSNS. The lesion was negative for any fusion genes, as previously reported. The long-term progression of BSNS is not clear. This case appears to be the first reported recurrence of BSNS with cerebral hemorrhaging. Biphenotypic sinonasal sarcoma should be considered to need long-term follow-up.

Original languageEnglish
Pages (from-to)E1-E2
JournalJournal of Craniofacial Surgery
Issue number1
Publication statusPublished - 2019

All Science Journal Classification (ASJC) codes

  • Surgery
  • Otorhinolaryngology


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