@inbook{38aaaec8c29147a18623b1ea4c3e05c4,
title = "Recent Advances in Molecular Mechanisms of Taste Signaling and Modifying",
abstract = "The sense of taste conveys crucial information about the quality and nutritional value of foods before it is ingested. Taste signaling begins with taste cells via taste receptors in oral cavity. Activation of these receptors drives the transduction systems in taste receptor cells. Then particular transmitters are released from the taste cells and activate corresponding afferent gustatory nerve fibers. Recent studies have revealed that taste sensitivities are defined by distinct taste receptors and modulated by endogenous humoral factors in a specific group of taste cells. Such peripheral taste generations and modifications would directly influence intake of nutritive substances. This review will highlight current understanding of molecular mechanisms for taste reception, signal transduction in taste bud cells, transmission between taste cells and nerves, regeneration from taste stem cells, and modification by humoral factors at peripheral taste organs.",
author = "Noriatsu Shigemura and Yuzo Ninomiya",
note = "Funding Information: This work was supported in part by Grants-in-Aid 24659828 and 15K11044 (N.S.), 23249081 and 15H02571 (Y.N.) for Scientific Research from the Ministry of Education, Culture, Sports, Science. Publisher Copyright: {\textcopyright} 2016 Elsevier Inc.",
year = "2016",
doi = "10.1016/bs.ircmb.2015.12.004",
language = "English",
series = "International Review of Cell and Molecular Biology",
publisher = "Elsevier Inc.",
pages = "71--106",
booktitle = "International Review of Cell and Molecular Biology",
address = "United States",
}