Rapidly progressive pulmonary veno-occlusive disease in an infant with Down syndrome

Jun Muneuchi; Shinichiro Oda; Daisuke Shimizu

doi:10.1017/S1047951117000397

Rapidly progressive pulmonary veno-occlusive disease in an infant with Down syndrome

Jun Muneuchi, Shinichiro Oda, Daisuke Shimizu

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

A 4-month-old girl with Down syndrome showed unexpected deterioration of pulmonary hypertension. Despite aggressive pulmonary vasodilation therapy, the patient died at 5 months of age. Lung autopsy showed that the pulmonary veins were obliterated by intimal fibrous thickening, and the media of the veins was arterialised with an increase in elastic fibres. Pulmonary veno-occlusive disease should be considered in the management of individuals with Down syndrome.

Original language	English
Pages (from-to)	1402-1405
Number of pages	4
Journal	Cardiology in the Young
Volume	27
Issue number	7
DOIs	https://doi.org/10.1017/S1047951117000397
Publication status	Published - Sept 1 2017
Externally published	Yes

All Science Journal Classification (ASJC) codes

Pediatrics, Perinatology, and Child Health
Cardiology and Cardiovascular Medicine

Access to Document

10.1017/S1047951117000397

Cite this

@article{803a1a3283014b439ffd272f9de49fae,

title = "Rapidly progressive pulmonary veno-occlusive disease in an infant with Down syndrome",

abstract = "A 4-month-old girl with Down syndrome showed unexpected deterioration of pulmonary hypertension. Despite aggressive pulmonary vasodilation therapy, the patient died at 5 months of age. Lung autopsy showed that the pulmonary veins were obliterated by intimal fibrous thickening, and the media of the veins was arterialised with an increase in elastic fibres. Pulmonary veno-occlusive disease should be considered in the management of individuals with Down syndrome.",

author = "Jun Muneuchi and Shinichiro Oda and Daisuke Shimizu",

note = "Publisher Copyright: {\textcopyright} 2017 Cambridge University Press.",

year = "2017",

month = sep,

day = "1",

doi = "10.1017/S1047951117000397",

language = "English",

volume = "27",

pages = "1402--1405",

journal = "Cardiology in the Young",

issn = "1047-9511",

publisher = "Cambridge University Press",

number = "7",

}

TY - JOUR

T1 - Rapidly progressive pulmonary veno-occlusive disease in an infant with Down syndrome

AU - Muneuchi, Jun

AU - Oda, Shinichiro

AU - Shimizu, Daisuke

PY - 2017/9/1

Y1 - 2017/9/1

N2 - A 4-month-old girl with Down syndrome showed unexpected deterioration of pulmonary hypertension. Despite aggressive pulmonary vasodilation therapy, the patient died at 5 months of age. Lung autopsy showed that the pulmonary veins were obliterated by intimal fibrous thickening, and the media of the veins was arterialised with an increase in elastic fibres. Pulmonary veno-occlusive disease should be considered in the management of individuals with Down syndrome.

AB - A 4-month-old girl with Down syndrome showed unexpected deterioration of pulmonary hypertension. Despite aggressive pulmonary vasodilation therapy, the patient died at 5 months of age. Lung autopsy showed that the pulmonary veins were obliterated by intimal fibrous thickening, and the media of the veins was arterialised with an increase in elastic fibres. Pulmonary veno-occlusive disease should be considered in the management of individuals with Down syndrome.

UR - http://www.scopus.com/inward/record.url?scp=85026865327&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85026865327&partnerID=8YFLogxK

U2 - 10.1017/S1047951117000397

DO - 10.1017/S1047951117000397

M3 - Article

C2 - 28782495

AN - SCOPUS:85026865327

SN - 1047-9511

VL - 27

SP - 1402

EP - 1405

JO - Cardiology in the Young

JF - Cardiology in the Young

IS - 7

ER -

Rapidly progressive pulmonary veno-occlusive disease in an infant with Down syndrome

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this