Rapid growth of metastatic brain tumor from gastric undifferentiated pleomorphic sarcoma: A case report

Kenji Miki, Koji Yoshimoto, Yuichi Yamada, Akira Kabashima, Daisuke Kuga, Yoshinao Oda, Koji Iihara

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Background: Brain metastasis from undifferentiated pleomorphic sarcoma (UPS) is a rare occurrence, and its clinical course is little known. In this report, we investigate a case of a rapidly growing brain metastasis from gastric UPS. Case Description: An 82-year-old man with a known gastric tumor, pathologically compatible with UPS, underwent partial gastrectomy at an outside facility. 3 months later, a 4-cm brain tumor was detected, which was completely resected. The patient was diagnosed with metastatic tumor from previously treated gastric UPS. Within 2 months of the initial resection, a large recurrent mass was detected in the same location, which was again removed. Although the patient underwent radiotherapy and chemotherapy for other metastatic tumors, he died 5 months after the second craniotomy. Conclusions: Brain metastasis from gastric UPS is rare and difficult to treat. Although aggressive treatment, such as surgical intervention, may improve patient survival in some cases, the timing of treatment is challenging because cerebral metastasis rapidly grows and and patients frequently suffer from synchronous systematic metastasis. Therefore, early detection and close follow-up of rapidly progressing brain metastasis are important to improve treatment outcomes.

Original languageEnglish
Pages (from-to)1-4
Number of pages4
JournalSurgical Neurology International
Issue number74
Publication statusPublished - Apr 24 2019

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology


Dive into the research topics of 'Rapid growth of metastatic brain tumor from gastric undifferentiated pleomorphic sarcoma: A case report'. Together they form a unique fingerprint.

Cite this