Various devices are developed to obtain information of odor for crisis evasion in dangerous situation. However, the improvement of sensing methodology is lagging. Therefore, some novel odor sensors with high sensitivity, selectivity and short response time are required. Gas detection based on surface enhanced Raman scattering (SERS) is a promising technology to realize such sensor. We developed a sandwich structured SERS substrate with an organic layer, which was placed between an Au thin layer and a gold nano particles (AuNPs) layer. Furthermore, the organic layer was reconfigured to molecularly imprinted polymer (MIP) for selective gas detection. Raman spectrum obtained with a MIP-SERS substrate shows the appearance of peak based on 2-phenylethanol that is targeted gas molecule. Compared with non-imprinted polymer (NIP), MIP substrate showed stronger SERS signals.