Radical induced protein crystallization by radical amplification microfluidic chip

T. Kobayashi; Y. Yamanishi

doi:10.1109/TRANSDUCERS.2015.7181019

Radical induced protein crystallization by radical amplification microfluidic chip

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

The paper reports plasma induced radical concentration microfluidic chip and radical induced protein crystallization. The novelty of our work is collection and concentration of radical species and which is confirmed by ESR (Electron Spin Resonance) measurement. Formation of bubbles which has a relatively large surface area accelerates the production of radical species at air-liquid interface and these bubbles are concentrated by the circulating flow in the microfluidic chip. It was also confirmed that the radical-induced protein crystal are produced with increasing of the circulation time. This microfluidic chip contributes to the protein crystal production and bio-medical applications.

Original language	English
Title of host publication	2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	700-703
Number of pages	4
ISBN (Electronic)	9781479989553
DOIs	https://doi.org/10.1109/TRANSDUCERS.2015.7181019
Publication status	Published - Aug 5 2015
Externally published	Yes
Event	18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015 - Anchorage, United States Duration: Jun 21 2015 → Jun 25 2015

Publication series

Name	2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015

Other

Other	18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015
Country/Territory	United States
City	Anchorage
Period	6/21/15 → 6/25/15

All Science Journal Classification (ASJC) codes

Instrumentation
Electrical and Electronic Engineering

Access to Document

10.1109/TRANSDUCERS.2015.7181019

Cite this

Kobayashi, T., & Yamanishi, Y. (2015). Radical induced protein crystallization by radical amplification microfluidic chip. In 2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015 (pp. 700-703). Article 7181019 (2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/TRANSDUCERS.2015.7181019

Radical induced protein crystallization by radical amplification microfluidic chip. / Kobayashi, T.; Yamanishi, Y.
2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015. Institute of Electrical and Electronics Engineers Inc., 2015. p. 700-703 7181019 (2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Kobayashi, T & Yamanishi, Y 2015, Radical induced protein crystallization by radical amplification microfluidic chip. in 2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015., 7181019, 2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015, Institute of Electrical and Electronics Engineers Inc., pp. 700-703, 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015, Anchorage, United States, 6/21/15. https://doi.org/10.1109/TRANSDUCERS.2015.7181019

Kobayashi T, Yamanishi Y. Radical induced protein crystallization by radical amplification microfluidic chip. In 2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015. Institute of Electrical and Electronics Engineers Inc. 2015. p. 700-703. 7181019. (2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015). doi: 10.1109/TRANSDUCERS.2015.7181019

Kobayashi, T. ; Yamanishi, Y. / Radical induced protein crystallization by radical amplification microfluidic chip. 2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015. Institute of Electrical and Electronics Engineers Inc., 2015. pp. 700-703 (2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015).

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abstract = "The paper reports plasma induced radical concentration microfluidic chip and radical induced protein crystallization. The novelty of our work is collection and concentration of radical species and which is confirmed by ESR (Electron Spin Resonance) measurement. Formation of bubbles which has a relatively large surface area accelerates the production of radical species at air-liquid interface and these bubbles are concentrated by the circulating flow in the microfluidic chip. It was also confirmed that the radical-induced protein crystal are produced with increasing of the circulation time. This microfluidic chip contributes to the protein crystal production and bio-medical applications.",

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AB - The paper reports plasma induced radical concentration microfluidic chip and radical induced protein crystallization. The novelty of our work is collection and concentration of radical species and which is confirmed by ESR (Electron Spin Resonance) measurement. Formation of bubbles which has a relatively large surface area accelerates the production of radical species at air-liquid interface and these bubbles are concentrated by the circulating flow in the microfluidic chip. It was also confirmed that the radical-induced protein crystal are produced with increasing of the circulation time. This microfluidic chip contributes to the protein crystal production and bio-medical applications.

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Radical induced protein crystallization by radical amplification microfluidic chip

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