TY - GEN
T1 - Quantitative evaluation of insulating performance on silicon nanobiodevices for fully integrated nanopore single DNA sequencing
AU - Sano, Mamiko
AU - Yasui, Takao
AU - Kaji, Noritada
AU - Taniguchi, Masateru
AU - Kawai, Tomoji
AU - Baba, Yoshinobu
N1 - Publisher Copyright:
© 14CBMS.
PY - 2014
Y1 - 2014
N2 - To realize a silicon-based semiconductor nanopore DNA sequencer, we have quantitatively evaluated insulating performance of silicon-based nanoslit array structures to stretch a random-coiled DNA molecule by electrokinetic force as a step prior to nanopore DNA sequencing. We found critical electric fields which trigger electric breakdown as a function of buffer concentration and successfully observed a single DNA molecular stretching in the nanoslit array structures under the explored conditions.
AB - To realize a silicon-based semiconductor nanopore DNA sequencer, we have quantitatively evaluated insulating performance of silicon-based nanoslit array structures to stretch a random-coiled DNA molecule by electrokinetic force as a step prior to nanopore DNA sequencing. We found critical electric fields which trigger electric breakdown as a function of buffer concentration and successfully observed a single DNA molecular stretching in the nanoslit array structures under the explored conditions.
UR - http://www.scopus.com/inward/record.url?scp=84941687198&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84941687198&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84941687198
T3 - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
SP - 1479
EP - 1481
BT - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PB - Chemical and Biological Microsystems Society
T2 - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
Y2 - 26 October 2014 through 30 October 2014
ER -