TY - JOUR
T1 - QOL-enhancing surgery for patients with HER2-positive metastatic breast cancer
AU - Kai, Masaya
AU - Kubo, Makoto
AU - Kawaji, Hitomi
AU - Kurata, Kanako
AU - Mori, Hitomi
AU - Yamada, Mai
AU - Nakamura, Masafumi
N1 - Publisher Copyright:
© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.
PY - 2019/6/1
Y1 - 2019/6/1
N2 - The role of the resection of primary tumour in stage IV breast cancer is unclear. Systemic therapy is recommended to prolong the survival and improve the quality of life (QOL). However, even if the systemic therapy is effective to control distant metastasis, sometimes the local lesion worsens, especially in the aggressive subtypes such as HER2-positive breast cancer. In uncontrollable tumours, the wound bed can bleed, weep and get infected, leading to dismal QOL. Our study describes two cases of patients with HER2-positive stage IV breast cancer who underwent palliative mastectomy which resulted in improvement of QOL. Local tumour control through palliative mastectomy can be beneficial for symptomatic aggressive patients with HER2-positive breast cancer to improve their QOL.
AB - The role of the resection of primary tumour in stage IV breast cancer is unclear. Systemic therapy is recommended to prolong the survival and improve the quality of life (QOL). However, even if the systemic therapy is effective to control distant metastasis, sometimes the local lesion worsens, especially in the aggressive subtypes such as HER2-positive breast cancer. In uncontrollable tumours, the wound bed can bleed, weep and get infected, leading to dismal QOL. Our study describes two cases of patients with HER2-positive stage IV breast cancer who underwent palliative mastectomy which resulted in improvement of QOL. Local tumour control through palliative mastectomy can be beneficial for symptomatic aggressive patients with HER2-positive breast cancer to improve their QOL.
UR - http://www.scopus.com/inward/record.url?scp=85053905806&partnerID=8YFLogxK
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U2 - 10.1136/bmjspcare-2018-001622
DO - 10.1136/bmjspcare-2018-001622
M3 - Article
C2 - 30254019
AN - SCOPUS:85053905806
SN - 2045-435X
VL - 9
SP - 151
EP - 154
JO - BMJ Supportive and Palliative Care
JF - BMJ Supportive and Palliative Care
IS - 2
ER -
