Proliferation and adhesion of periodontal ligament cells on synthetic biominerals

Junko Hatakeyama, Yuji Hatakeyama, Ichiro Takahashi, Osamu Suzuki, Yasuyuki Sasano

Research output: Contribution to journalReview articlepeer-review


The present study was designed to investigate the proliferation and expression of adhesion and extracellular matrix molecules in periodontal ligament (PDL) cells cultured on synthetic calcium phosphates, octacalcium phosphate and its hydrolyzed apatitic product comparing with those cultured on collagen and plastic substrates. Our results suggest that PDL cells expressing various integrins are attached to the synthetic biomineral analogues through collagens and fibronectin produced by themselves. These calcium phosphates relevant to biomineralization may support proliferation and adhesion of PDL cells in vivo.

Original languageEnglish
Pages (from-to)328-329
Number of pages2
JournalInternational Congress Series
Publication statusPublished - Sept 2005
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Medicine


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