TY - JOUR
T1 - Primary non-Hodgkin's lymphoma of the lacrimal sac
T2 - A case report and a review of the literature
AU - Nakamura, Katsumasa
AU - Uehara, Satoru
AU - Omagari, Junichi
AU - Kunitake, Naonobu
AU - Kimura, Masahiko
AU - Makino, Yasuhiro
AU - Ishigami, Kousei
AU - Masuda, Kouji
PY - 1997/12/1
Y1 - 1997/12/1
N2 - BACKGROUND. Primary non-Hodgkin's lymphoma of the lacrimal sac is extremely rare, with most reported cases representing secondary involvement of a systemic malignancy. METHODS. The clinical record of a 70-year-old female who presented with epiphora and swelling of the lacrimal sac area is described. A review of the literature of patients with primary lacrimal sac lymphoma also is presented. RESULTS. Computed tomography demonstrated a lacrimal sac mass involving the nasolacrimal canal. Histopathologic examination of a biopsy specimen revealed a diffuse large cell lymphoma. Using immunohistologic staining, the tumor was a B-cell type, similar to those described in the literature. The patient was treated with 50 gray of irradiation and chemotherapy with cyclophosphamide, doxorubicin, vincristine, and prednisone. The patient remained free of lymphoma 26 months after initial treatment. An ocular examination was unremarkable except for epiphora. CONCLUSIONS. Radiotherapy and/or chemotherapy can treat localized lymphoma of the lacrimal sac successfully.
AB - BACKGROUND. Primary non-Hodgkin's lymphoma of the lacrimal sac is extremely rare, with most reported cases representing secondary involvement of a systemic malignancy. METHODS. The clinical record of a 70-year-old female who presented with epiphora and swelling of the lacrimal sac area is described. A review of the literature of patients with primary lacrimal sac lymphoma also is presented. RESULTS. Computed tomography demonstrated a lacrimal sac mass involving the nasolacrimal canal. Histopathologic examination of a biopsy specimen revealed a diffuse large cell lymphoma. Using immunohistologic staining, the tumor was a B-cell type, similar to those described in the literature. The patient was treated with 50 gray of irradiation and chemotherapy with cyclophosphamide, doxorubicin, vincristine, and prednisone. The patient remained free of lymphoma 26 months after initial treatment. An ocular examination was unremarkable except for epiphora. CONCLUSIONS. Radiotherapy and/or chemotherapy can treat localized lymphoma of the lacrimal sac successfully.
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U2 - 10.1002/(SICI)1097-0142(19971201)80:11<2151::AID-CNCR15>3.0.CO;2-Y
DO - 10.1002/(SICI)1097-0142(19971201)80:11<2151::AID-CNCR15>3.0.CO;2-Y
M3 - Article
C2 - 9392338
AN - SCOPUS:0030691954
SN - 0008-543X
VL - 80
SP - 2151
EP - 2155
JO - Cancer
JF - Cancer
IS - 11
ER -
