Primary intracerebral malignant melanoma with leptomeningeal spread, extradural extension and lung metastasis

I. Kobayashi; H. Oka; N. Kawano; A. Kurata; S. Tanaka; S. Utsuki; S. Suzuki; Y. Ishihara; K. Fujii

Primary intracerebral malignant melanoma with leptomeningeal spread, extradural extension and lung metastasis

I. Kobayashi, H. Oka, N. Kawano, A. Kurata, S. Tanaka, S. Utsuki, S. Suzuki, Y. Ishihara, K. Fujii

Research output: Contribution to journal › Article › peer-review

Abstract

A rare primary intracerebral solitary malignant melanoma with extracranial metastasis is reported. The patient was a 66-year-old man who was revealed to have a tumor in the right temporal lobe by MRI. The tumor was totally resected and the histopathological diagnosis was malignant melanoma. Despite postoperative treatment with chemo-radiotherapy, tumor recurred with multiple subarachnoid dissemination. Complete autopsy showed marked leptomeningeal dissemination of tumor in the cerebro-spinal compartment. In the outside of the central nervous system, a microscopic metastatic nodule was found in the right lung. Metastatic tumor in the spinal cord showed the extradural extension which might have led to hematogenous metastasis to the lung.

Original language	English
Pages (from-to)	43-45
Number of pages	3
Journal	Clinical Neuropathology
Volume	20
Issue number	1
Publication status	Published - 2001
Externally published	Yes

All Science Journal Classification (ASJC) codes

Pathology and Forensic Medicine
Neurology
Clinical Neurology

Cite this

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title = "Primary intracerebral malignant melanoma with leptomeningeal spread, extradural extension and lung metastasis",

abstract = "A rare primary intracerebral solitary malignant melanoma with extracranial metastasis is reported. The patient was a 66-year-old man who was revealed to have a tumor in the right temporal lobe by MRI. The tumor was totally resected and the histopathological diagnosis was malignant melanoma. Despite postoperative treatment with chemo-radiotherapy, tumor recurred with multiple subarachnoid dissemination. Complete autopsy showed marked leptomeningeal dissemination of tumor in the cerebro-spinal compartment. In the outside of the central nervous system, a microscopic metastatic nodule was found in the right lung. Metastatic tumor in the spinal cord showed the extradural extension which might have led to hematogenous metastasis to the lung.",

author = "I. Kobayashi and H. Oka and N. Kawano and A. Kurata and S. Tanaka and S. Utsuki and S. Suzuki and Y. Ishihara and K. Fujii",

note = "Funding Information: A part of this study were supported by Grants-in-Aid for the Health Sciences Research Grants for the Research on Pharmaceutical and Medical Safety from the Ministry of Health and Welfare of Japan and the Research on Health Sciences Focusing on Drug Innovation from Japan Health Sciences Foundation.",

year = "2001",

language = "English",

volume = "20",

pages = "43--45",

journal = "Clinical Neuropathology",

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TY - JOUR

T1 - Primary intracerebral malignant melanoma with leptomeningeal spread, extradural extension and lung metastasis

AU - Kobayashi, I.

AU - Oka, H.

AU - Kawano, N.

AU - Kurata, A.

AU - Tanaka, S.

AU - Utsuki, S.

AU - Suzuki, S.

AU - Ishihara, Y.

AU - Fujii, K.

N1 - Funding Information: A part of this study were supported by Grants-in-Aid for the Health Sciences Research Grants for the Research on Pharmaceutical and Medical Safety from the Ministry of Health and Welfare of Japan and the Research on Health Sciences Focusing on Drug Innovation from Japan Health Sciences Foundation.

PY - 2001

Y1 - 2001

N2 - A rare primary intracerebral solitary malignant melanoma with extracranial metastasis is reported. The patient was a 66-year-old man who was revealed to have a tumor in the right temporal lobe by MRI. The tumor was totally resected and the histopathological diagnosis was malignant melanoma. Despite postoperative treatment with chemo-radiotherapy, tumor recurred with multiple subarachnoid dissemination. Complete autopsy showed marked leptomeningeal dissemination of tumor in the cerebro-spinal compartment. In the outside of the central nervous system, a microscopic metastatic nodule was found in the right lung. Metastatic tumor in the spinal cord showed the extradural extension which might have led to hematogenous metastasis to the lung.

AB - A rare primary intracerebral solitary malignant melanoma with extracranial metastasis is reported. The patient was a 66-year-old man who was revealed to have a tumor in the right temporal lobe by MRI. The tumor was totally resected and the histopathological diagnosis was malignant melanoma. Despite postoperative treatment with chemo-radiotherapy, tumor recurred with multiple subarachnoid dissemination. Complete autopsy showed marked leptomeningeal dissemination of tumor in the cerebro-spinal compartment. In the outside of the central nervous system, a microscopic metastatic nodule was found in the right lung. Metastatic tumor in the spinal cord showed the extradural extension which might have led to hematogenous metastasis to the lung.

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ER -

Primary intracerebral malignant melanoma with leptomeningeal spread, extradural extension and lung metastasis

Abstract

All Science Journal Classification (ASJC) codes

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