Primary Human Herpesvirus 6 Infection in an Adult

David J. Morris, Anne L. Appleton, Lisbet Sviland, C. A. Schmidt, F. F. Wilborn, W. Siegert, Richard Cone, Lawrence Corey, Robert Hackman, Koichi Akashi, Yoshito Eizuru, Yoshiaki Sumiyoshi

Research output: Contribution to journalLetterpeer-review

9 Citations (Scopus)


To the Editor: Akashi et al. (July 15 issue)1 reported seroconversion to human herpesvirus 6 (HHV-6) positivity in a patient with an infectious mononucleosis-like syndrome, and Cone et al. (July 15 issue)2 detected high levels of HHV-6 genome in the lungs of recipients of bone marrow transplants who had idiopathic pneumonitis. In neither instance did the data prove that the virus caused the disease being studied. In the first report, the observations could have reflected recurrent HHV-6 infection coincident with signs and symptoms unrelated to the virus1,3. The authors interpreted the serologic findings (IgG seroconversion with no IgM…

Original languageEnglish
Pages (from-to)1817-1819
Number of pages3
JournalNew England Journal of Medicine
Issue number24
Publication statusPublished - Dec 9 1993

All Science Journal Classification (ASJC) codes

  • General Medicine


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