TY - JOUR
T1 - Prevalence and Risk Factors for Polypoidal Choroidal Vasculopathy in a General Japanese Population
T2 - The Hisayama Study
AU - Fujiwara, Kohta
AU - Yasuda, Miho
AU - Hata, Jun
AU - Oshima, Yuji
AU - Hashimoto, Sawako
AU - Yoshitomi, Takeshi
AU - Kiyohara, Yutaka
AU - Ishibashi, Tatsuro
AU - Ninomiya, Toshiharu
AU - Sonoda, Koh Hei
N1 - Funding Information:
This work was supported by the Japanese Ministry of Education, Culture, Sports, Science, and Technology [grant number 18K09412 to MY], [grant number 18K16960 to KF].
Publisher Copyright:
©, © Taylor & Francis.
PY - 2018/8/18
Y1 - 2018/8/18
N2 - Purpose: To estimate the prevalence and risk factors for polypoidal choroidal vasculopathy (PCV) in a general Japanese population. Methods: This population-based, cross-sectional study was conducted in 2007 with subjects from the Hisayama Study. Of the 3,648 residents in Hisayama, Japan, 2,663 who were ≥ 50 years old were enrolled in this study. The characteristics of PCV were determined by fundus examination or based on indocyanine green and fluorescein angiographic findings. We evaluated the contributions of the risk factors for PCV. Results: Among the 207 participants with age-related macular degeneration (AMD), 174 (6.5%) had early AMD, and 33 (1.2%) had late AMD, including 10 participants with PCV (0.4%). Male and smoking habit were significant risk factors for the development of PCV. Conclusions: The prevalence of PCV is higher among Japanese subjects than Caucasians in Western countries. Male gender and smoking habit were significant risk factors for PCV in a general Japanese population.
AB - Purpose: To estimate the prevalence and risk factors for polypoidal choroidal vasculopathy (PCV) in a general Japanese population. Methods: This population-based, cross-sectional study was conducted in 2007 with subjects from the Hisayama Study. Of the 3,648 residents in Hisayama, Japan, 2,663 who were ≥ 50 years old were enrolled in this study. The characteristics of PCV were determined by fundus examination or based on indocyanine green and fluorescein angiographic findings. We evaluated the contributions of the risk factors for PCV. Results: Among the 207 participants with age-related macular degeneration (AMD), 174 (6.5%) had early AMD, and 33 (1.2%) had late AMD, including 10 participants with PCV (0.4%). Male and smoking habit were significant risk factors for the development of PCV. Conclusions: The prevalence of PCV is higher among Japanese subjects than Caucasians in Western countries. Male gender and smoking habit were significant risk factors for PCV in a general Japanese population.
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U2 - 10.1080/08820538.2018.1506483
DO - 10.1080/08820538.2018.1506483
M3 - Article
C2 - 30084710
AN - SCOPUS:85052062744
SN - 0882-0538
VL - 33
SP - 813
EP - 819
JO - Seminars in Ophthalmology
JF - Seminars in Ophthalmology
IS - 6
ER -