TY - JOUR
T1 - Presence of mitochondrial-DNA-like sequences in the human nuclear DNA
AU - Tsuzuki, Teruhisa
AU - Nomiyama, Hisayuki
AU - Setoyama, Chiaki
AU - Maeda, Shuichiro
AU - Shimada, Kazunori
N1 - Funding Information:
We thank Drs. M. Nakayama and M. Maeyama, Department of Obstetrics and Gynecology, Kuma-moto University, for providing of the human placenta and M. Ohara for reading the manuscript. This work was supported by a Grant-in-Aid for Special Project Research from the Ministry of Education, Science and Culture, Japan.
PY - 1983/11
Y1 - 1983/11
N2 - Two λ phage clones carrying contiguous human nuclear DNA sequences with extensive homology to non-contiguous human mitochondrial 16S ribosomal RNA sequences were isolated from a human gene library. The one clone carried mitochondrial-DNA(mtDNA)-like sequences flanked with two kinds of repetitive nuclear DNA sequences and the other carried mtDNA-like sequences, between unique nuclear DNA sequences and repetitive DNA sequences of Alu-family. These results demonstrate that mtDNA-like sequences are present in human nuclear DNA.
AB - Two λ phage clones carrying contiguous human nuclear DNA sequences with extensive homology to non-contiguous human mitochondrial 16S ribosomal RNA sequences were isolated from a human gene library. The one clone carried mitochondrial-DNA(mtDNA)-like sequences flanked with two kinds of repetitive nuclear DNA sequences and the other carried mtDNA-like sequences, between unique nuclear DNA sequences and repetitive DNA sequences of Alu-family. These results demonstrate that mtDNA-like sequences are present in human nuclear DNA.
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U2 - 10.1016/0378-1119(83)90226-3
DO - 10.1016/0378-1119(83)90226-3
M3 - Article
C2 - 6662364
AN - SCOPUS:0021019218
SN - 0378-1119
VL - 25
SP - 223
EP - 229
JO - Gene
JF - Gene
IS - 2-3
ER -