Preparation of perfluorocarbon/fluoroalkyl polymer nanodroplets for cancer-targeted ultrasound contrast agents

Masamichi Nishihara; Kenji Imai; Masayuki Yokoyama

doi:10.1246/cl.2009.556

Preparation of perfluorocarbon/fluoroalkyl polymer nanodroplets for cancer-targeted ultrasound contrast agents

Masamichi Nishihara, Kenji Imai, Masayuki Yokoyama

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Perfluorocarbon (PFC) nanodroplets formed from PEG-bpoly(fluoroheptyl aspartate) were developed for a cancer-targeted ultrasound (US) contrast agent. 10% esterifed fluoroalkyl polymer (F10) was the optimal composition for PFC solubilization in aqueous solution. PFC/F10 nanodroplets showed echogenicity with US irradiation, and long-term stability of PFC nanodroplets at 4 °C was confirmed.

Original language	English
Pages (from-to)	556-557
Number of pages	2
Journal	Chemistry Letters
Volume	38
Issue number	6
DOIs	https://doi.org/10.1246/cl.2009.556
Publication status	Published - 2009
Externally published	Yes

All Science Journal Classification (ASJC) codes

Chemistry(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1246/cl.2009.556

Cite this

@article{60704e2496a94951beba90fffdcde23e,

title = "Preparation of perfluorocarbon/fluoroalkyl polymer nanodroplets for cancer-targeted ultrasound contrast agents",

abstract = "Perfluorocarbon (PFC) nanodroplets formed from PEG-bpoly(fluoroheptyl aspartate) were developed for a cancer-targeted ultrasound (US) contrast agent. 10% esterifed fluoroalkyl polymer (F10) was the optimal composition for PFC solubilization in aqueous solution. PFC/F10 nanodroplets showed echogenicity with US irradiation, and long-term stability of PFC nanodroplets at 4 °C was confirmed.",

author = "Masamichi Nishihara and Kenji Imai and Masayuki Yokoyama",

year = "2009",

doi = "10.1246/cl.2009.556",

language = "English",

volume = "38",

pages = "556--557",

journal = "Chemistry Letters",

issn = "0366-7022",

publisher = "The Chemical Society of Japan",

number = "6",

}

TY - JOUR

T1 - Preparation of perfluorocarbon/fluoroalkyl polymer nanodroplets for cancer-targeted ultrasound contrast agents

AU - Nishihara, Masamichi

AU - Imai, Kenji

AU - Yokoyama, Masayuki

PY - 2009

Y1 - 2009

N2 - Perfluorocarbon (PFC) nanodroplets formed from PEG-bpoly(fluoroheptyl aspartate) were developed for a cancer-targeted ultrasound (US) contrast agent. 10% esterifed fluoroalkyl polymer (F10) was the optimal composition for PFC solubilization in aqueous solution. PFC/F10 nanodroplets showed echogenicity with US irradiation, and long-term stability of PFC nanodroplets at 4 °C was confirmed.

AB - Perfluorocarbon (PFC) nanodroplets formed from PEG-bpoly(fluoroheptyl aspartate) were developed for a cancer-targeted ultrasound (US) contrast agent. 10% esterifed fluoroalkyl polymer (F10) was the optimal composition for PFC solubilization in aqueous solution. PFC/F10 nanodroplets showed echogenicity with US irradiation, and long-term stability of PFC nanodroplets at 4 °C was confirmed.

UR - http://www.scopus.com/inward/record.url?scp=67650459345&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=67650459345&partnerID=8YFLogxK

U2 - 10.1246/cl.2009.556

DO - 10.1246/cl.2009.556

M3 - Article

AN - SCOPUS:67650459345

SN - 0366-7022

VL - 38

SP - 556

EP - 557

JO - Chemistry Letters

JF - Chemistry Letters

IS - 6

ER -

Preparation of perfluorocarbon/fluoroalkyl polymer nanodroplets for cancer-targeted ultrasound contrast agents

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this