Preparation of nanometer-scale rod array of hydroxyapatite crystal

Satoshi Hayakawa, Yaqi Li, Kanji Tsuru, Akiyoshi Osaka, Eiji Fujii, Koji Kawabata

Research output: Contribution to journalArticlepeer-review

48 Citations (Scopus)


Fabrication of nano- or micro-structured scaffolds to mimic structural and three-dimensional details of natural bone or teeth has been the subject of much interest, and this study proposes a new strategy for self-assembling one-dimensional hydroxyapatite (HAp) nanorods into organized superstructures. A nanometer-scale rod array of HAp having preferred orientation to the c-axis was successfully prepared simply by soaking calcium-containing silicate glass substrates in Na2HPO4 aqueous solution at 80 °C for various periods. Those HAp rods grew perpendicularly to the glass surface, and the crystallites covered the glass surface uniformly, resulting in a "dental enamel-like" rod array structure consisting of "pine-leaf-like" structure units.

Original languageEnglish
Pages (from-to)2152-2160
Number of pages9
JournalActa Biomaterialia
Issue number6
Publication statusPublished - Jul 2009

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biomaterials
  • Biochemistry
  • Biomedical Engineering
  • Molecular Biology


Dive into the research topics of 'Preparation of nanometer-scale rod array of hydroxyapatite crystal'. Together they form a unique fingerprint.

Cite this