TY - GEN
T1 - Preparation, characterization and biological assessment of bioactive and mesoporous silica nanoparticle coatings for bone regeneration
AU - Chen, Song
AU - Tsuru, Kanji
AU - Hayakawa, Satoshi
AU - Osaka, Akiyoshi
PY - 2008
Y1 - 2008
N2 - Bioactive porous silica particle coatings were fabricated on the stainless steel substrates as bone repairing implants to enhance the apatite deposition. The particles were prepared from tetraethoxysilane (TEOS) and cetyltrimethylammonium bromide (CTAB) via the sol-gel method and then calcined at 600°C for 2 h to produce the porous structure. Subsequently, the clean substrates were sequentially soaked in the chitosan, silica and calcium alginate solutions to obtain the chitosan/silica/calcium alginate coatings via the charged layer-by-layer deposition technique. The treated substrates deposited bioactive apatite when soaked in the Kokubo's simulated body fluid (SBF) and exhibited bioactivity. Thus, such bioactive porous silica coatings are applicable to the reservoirs for storing and releasing the bone factors.
AB - Bioactive porous silica particle coatings were fabricated on the stainless steel substrates as bone repairing implants to enhance the apatite deposition. The particles were prepared from tetraethoxysilane (TEOS) and cetyltrimethylammonium bromide (CTAB) via the sol-gel method and then calcined at 600°C for 2 h to produce the porous structure. Subsequently, the clean substrates were sequentially soaked in the chitosan, silica and calcium alginate solutions to obtain the chitosan/silica/calcium alginate coatings via the charged layer-by-layer deposition technique. The treated substrates deposited bioactive apatite when soaked in the Kokubo's simulated body fluid (SBF) and exhibited bioactivity. Thus, such bioactive porous silica coatings are applicable to the reservoirs for storing and releasing the bone factors.
UR - http://www.scopus.com/inward/record.url?scp=84872161434&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84872161434&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84872161434
SN - 9788880800842
T3 - A Global Road Map for Ceramic Materials and Technologies: Forecasting the Future of Ceramics, International Ceramic Federation - 2nd International Congress on Ceramics, ICC 2008, Final Programme
BT - A Global Road Map for Ceramic Materials and Technologies
T2 - 2nd International Congress on Ceramics, ICC 2008
Y2 - 29 June 2008 through 4 July 2008
ER -