Preoperative T staging of gastric cancer by multi-detector row computed tomography

Tomoki Makino, Yoshiyuki Fujiwara, Shuji Takiguchi, Takahiro Tsuboyama, Tonsok Kim, Youichirou Nushijima, Makoto Yamasaki, Hiroshi Miyata, Kiyokazu Nakajima, Masaki Mori, Yuichiro Doki

Research output: Contribution to journalArticlepeer-review

46 Citations (Scopus)


Background and Purpose: Preoperative T staging demands high accuracy, because it greatly influences subsequent therapies in advanced gastric cancer. Patients and Methods: 616 patients with gastric cancer underwent multi-detector row computed tomography (MDCT) before operation. The results were compared with operative and pathologic findings. Especially, we evaluated the correlations among the diagnostic accuracy of T staging and various clinicopathologic parameters by focusing on 276 patients who had detectable lesions by MDCT. Results: The overall diagnostic accuracy of preoperative T staging by MDCT was 90.9% (560/616). For each pathologic T stage, the accuracy was 95% for pT1, 76% for pT2-3, 92% for pT4a, and 75% for pT4b, respectively. Among the 276 patients, 239 (87%) were correctly staged by MDCT whereas 29 (11%) and 8 (3%) were over- or under-staged, respectively. Antral tumors (P = .045), and Borrmann type 1 tumors (P = .0001) were incorrectly T staged by MDCT, whereas differentiated type tumors tended to be over-staged. All patients with positive cytology (n = 12 cases) and peritoneal metastasis (n = 7 cases) diagnosed at laparotomy had been diagnosed as T4a or deeper by MDCT. The 5-year overall survival rates classified by preoperative T staging by MDCT (T1/T2-3/T4a/T4b) were 100%, 89%, 59%, and 31%, respectively, whereas those for each pT stage were 100%, 84%, 59%, and 19%. Conclusion: Preoperative T staging of gastric cancer by MDCT is highly accurate and could contribute to treatment strategies, particularly in advanced disease.

Original languageEnglish
Pages (from-to)672-679
Number of pages8
Issue number5
Publication statusPublished - May 2011
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Surgery


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