Pre- and post-operative chemoradiation therapies for pancreatic cancers

Osamu Ishikawa, Hiroaki Ohigashi, Hidetoshi Eguchi, Terumasa Yamada, Y. Sasaki, Shingi Imaoka, Kinji Nishiyama

Research output: Contribution to journalReview articlepeer-review


Due to a high incidence of local recurrence, the long-term outcome after resection of locally advanced pancreatic cancer is still pessimistic. Many previous reports showed that locoregional control was partly improved by intraoperative radiation or postoperative chemoradiation, while others suggested its insufficient effects for patients with R1- or R2-resections. Therefore some recent authors have recommended preoperative chemoradiation for more promising results in advanced pancreatic cancer. Since patient survival is influenced not only by local control but also by distant (the liver is the most common) metastases, we should develop other strategies that can prevent liver metastases, in addition to the combination of chemoradiation with sur-

Original languageEnglish
Pages (from-to)182-186
Number of pages5
JournalNippon Geka Gakkai zasshi
Issue number4
Publication statusPublished - Jul 2006
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Medicine


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